Commander Guou arrives from Chronos headquarters to lead the recovery of the Guyver Units. Meanwhile, Chronos Japan creates the Zoanoid "Zerububuse" in a final desperate attempt to eliminate the Guyver. To bait the trap for Sho, Mizuky is kidnapped and Sho once again must become the Guyver and face the challenge of Zeruububuse as well as the mysterious shadow, Guyver III.