Throughout the course of the 21th century, science evolved to the point of allowing humans with special skills to develop the art of magic. In 2095, Tatsuya Shiba and his sister Miyuki enroll at the Private Magic University Affiliated High School, but their different grades during the exam tests put them into divergent paths as while Miyuki is paired with the students with high magical skills, (labeled as "Blooms"), Tatsuya is assigned to study with the lower-skilled ones (labeled as "Weeds" in a derrogatory manner).